SCHEMBL17354801

SCHEMBL17354801

CN(CCO)CCOCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.49
HPGD P15428 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
RAB9A P51151 2/20 0.46
TSHR P16473 2/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ACHE P22303 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17354793 0.92 MAOB (0.51) MAOBACHE
SCHEMBL22123239 0.84 HPGD (0.53) MAOBHPGDNPSR1KMT2ARAB9A
SCHEMBL16306674 0.82 MAOB (0.67) MAOBACHE
SCHEMBL1463587 0.82 SMN1; SMN2 (0.55) HPGDNPSR1ALDH1A1MEN1KMT2A
SCHEMBL30274320 0.82 SMN1; SMN2 (0.55) HPGDNPSR1ALDH1A1MEN1KMT2A
SCHEMBL30274276 0.81 MAOB (0.47) MAOBHPGDNPSR1RAB9ATSHR
SCHEMBL23720311 0.81 SMN1; SMN2 (0.54) HPGDNPSR1ALDH1A1MEN1KMT2A
SCHEMBL19541802 0.81 SMN1; SMN2 (0.54) HPGDNPSR1ALDH1A1MEN1KMT2A
SCHEMBL230525 0.81 SMN1; SMN2 (0.54) HPGDNPSR1ALDH1A1MEN1KMT2A
SCHEMBL5371487 0.81 SMN1; SMN2 (0.54) HPGDNPSR1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2957563-A1 Separation material comprising phosphoryl choline derivatives Pentracor GmbH (DE) 2015-12-23 EP disclosed