Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.35 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17354858 | 0.89 | TK2 (0.42) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL17354860 | 0.86 | TK2 (0.44) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL15267268 | 0.82 | TK2 (0.41) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL11985231 | 0.82 | TK2 (0.41) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL17286266 | 0.82 | TK2 (0.34) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL15267269 | 0.81 | TK2 (0.40) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL11985225 | 0.81 | TK2 (0.40) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL11985226 | 0.80 | TK2 (0.39) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL15267271 | 0.80 | TK2 (0.39) | TK2TK1TYMPALDH1A1LMNA | |
| SCHEMBL17356776 | 0.79 | TK1 (0.41) | TK2TK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957567-A1 | NUCLEOSIDE AND NUCLEOTIDE, HAVING NITROGEN-CONTAINING HETERCYCLE STRUCTURE | Shionogi & Co., Ltd. (JP) | 2015-12-23 | — | — | EP | disclosed |