SCHEMBL17355396

SCHEMBL17355396

CCCCCCCCCCC(=O)Nc1ccc(C)c2ccccc12

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.75
CETP P11597 1/20 0.58
SOAT1 P35610 3/20 0.57
P2RX7 Q99572 1/20 0.55
SOAT2 O75908 1/20 0.53
GAA P10253 3/20 0.53
ALDH1A1 P00352 2/20 0.53
EPHX2 P34913 1/20 0.51
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
LMNA P02545 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968938 0.82 HDAC3 (0.74) EP300CETPSOAT1P2RX7ALDH1A1
SCHEMBL26624031 0.82 HDAC3 (0.74) EP300CETPSOAT1P2RX7ALDH1A1
SCHEMBL9395051 0.81 CETP (0.77) EP300CETPSOAT1P2RX7SOAT2
SCHEMBL5878480 0.81 CETP (0.77) EP300CETPSOAT1P2RX7SOAT2
SCHEMBL17751146 0.81 EP300 (0.68) EP300CETPSOAT1P2RX7SOAT2
SCHEMBL13876860 0.81 EP300 (0.68) EP300CETPSOAT1SOAT2GAA
SCHEMBL11446154 0.80 HDAC3 (0.77) EP300CETPSOAT1P2RX7ALDH1A1
SCHEMBL11327173 0.80 EP300 (0.84) EP300CETPSOAT1GAAALDH1A1
SCHEMBL12284940 0.80 ALDH1A1 (0.67) EP300CETPSOAT1GAAALDH1A1
SCHEMBL11499014 0.80 EP300 (0.62) EP300CETPSOAT1P2RX7SOAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045662-B1 Lithographic printing plate precursor and method of preparing lithographic printing plate FUJIFILM CORP (JP) 2015-12-23 EP disclosed