SCHEMBL17356239

SCHEMBL17356239

c1cc2sc3cc4sc(-c5cc6cc7c(cc6s5)sc5ccsc57)cc4cc3c2s1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356241 0.93 GPR35 (0.32) GPR35ADORA2AADORA1
SCHEMBL20191275 0.86
SCHEMBL9976814 0.83 GPR35 (0.36) GPR35
SCHEMBL16706170 0.81 CYP2A6 (0.35) GPR35
SCHEMBL1568157 0.80 GPR35 (0.39) GPR35
SCHEMBL14925154 0.79 GPR35 (0.36) GPR35
SCHEMBL20191273 0.78
SCHEMBL14925152 0.77 GPR35 (0.37) GPR35
SCHEMBL20910933 0.76 KDM4E (0.36) ADORA2AADORA1
SCHEMBL21166662 0.75 GPR35 (0.37) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10403828-B2 Organic compound, and organic thin film and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-09-03 US disclosed
US-9985222-B2 Organic compound, and organic thin film and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-29 US disclosed
US-9985222-B2 Organic compound, and organic thin film and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-29 US disclosed
US-20150372241-A1 ORGANIC COMPOUND, AND ORGANIC THIN FILM AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403828-B2 Organic compound, and organic thin film and electronic device OCIAD1, POU2F1, SLCO2A1 GPR35 4005/4885ADORA2A 4548/4885ADORA1 2122/4885
US-20150372241-A1 ORGANIC COMPOUND, AND ORGANIC THIN FILM AND ELECTRONIC DEVICE OCIAD1, POU2F1, SLCO2A1 GPR35 4005/4885ADORA2A 4548/4885ADORA1 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.