Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.69 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556937 | 0.84 | ELANE (0.71) | ELANEPRTN3 | |
| SCHEMBL3654752 | 0.84 | ELANE (0.71) | ELANEPRTN3 | |
| SCHEMBL23836711 | 0.83 | ELANE (0.65) | ELANEPRTN3 | |
| SCHEMBL10483720 | 0.82 | ELANE (1.00) | ELANEPRTN3 | |
| SCHEMBL22369614 | 0.81 | ELANE (0.86) | ELANEPRTN3 | |
| SCHEMBL21538650 | 0.81 | ELANE (0.89) | ELANEPRTN3 | |
| SCHEMBL16189796 | 0.80 | ELANE (0.76) | ELANEPRTN3 | |
| SCHEMBL3657615 | 0.80 | ELANE (0.76) | ELANEPRTN3 | |
| SCHEMBL3657617 | 0.80 | ELANE (0.76) | ELANEPRTN3 | |
| SCHEMBL4029716 | 0.80 | ELANE (0.65) | ELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580553-B2 | Thermally-activated self-immolative materials | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580553-B2 | Thermally-activated self-immolative materials | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160066553-A1 | CONTROLLED RELEASE OF CARBON DIOXIDE FROM SELF-IMMOLATIVE POLYMERS | UNIVERSITY OF WASHINGTON (US) | 2016-03-10 | — | — | US | disclosed |
| US-20150368403-A1 | THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368403-A1 | THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS | PARG, PAICS, LRBA | ELANE 3530/4885PRTN3 4143/4885NR4A2 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.