SCHEMBL3654752

SCHEMBL3654752

CC(C)(C)C(=O)Oc1ccc(COO)cc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.71
PRTN3 P24158 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18556937 0.86 ELANE (0.71) ELANEPRTN3
SCHEMBL17356345 0.84 ELANE (0.69) ELANEPRTN3
SCHEMBL10483720 0.83 ELANE (1.00) ELANEPRTN3
SCHEMBL22369614 0.82 ELANE (0.86) ELANEPRTN3
SCHEMBL21538650 0.82 ELANE (0.89) ELANEPRTN3
SCHEMBL3657615 0.81 ELANE (0.76) ELANEPRTN3
SCHEMBL16189796 0.81 ELANE (0.76) ELANEPRTN3
SCHEMBL3657617 0.81 ELANE (0.76) ELANEPRTN3
SCHEMBL4029716 0.81 ELANE (0.65) ELANEPRTN3
SCHEMBL17151769 0.81 ELANE (0.65) ELANEPRTN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076476-B2 Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits AVI BIOPHARMA, INC. (US) 2011-12-13 US disclosed
EP-2207779-A1 METHOD OF SYNTHESIS OF MORPHOLINO OLIGOMERS Avi Biopharma, Inc. (US) 2010-07-21 EP disclosed
WO-2009064471-A1 METHOD OF SYNTHESIS OF MORPHOLINO OLIGOMERS AVI BIOPHARMA, INC. (US) 2009-05-22 WO disclosed
US-20090131624-A1 SYNTHESIS OF MORPHOLINO OLIGOMERS USING DOUBLY PROTECTED GUANINE MORPHOLINO SUBUNITS AVI BIOPHARMA, INC. (US) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131624-A1 SYNTHESIS OF MORPHOLINO OLIGOMERS USING DOUBLY PROTECTED GUANINE MORPHOLINO SUBUNITS RNMT, O60361, PAM ELANE 4358/4885PRTN3 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.