SCHEMBL17356523

SCHEMBL17356523

Nc1nc2c(ncn2[C@@H]2O[C@H](CO[PH](=O)O)[C@H](O)C2O)c(=O)[nH]1

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.68
NT5E P21589 1/20 0.68
GSK3A P49840 2/20 0.64
RPS6KA3 P51812 2/20 0.64
MAPK14 Q16539 2/20 0.64
TGM2 P21980 1/20 0.63
PNP P00491 1/20 0.61
KRAS P01116 5/20 0.59
IMPDH2 P12268 4/20 0.58
IMPDH1 P20839 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24865920 1.00 HINT1 (0.68) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL2159124 1.00 HINT1 (0.68) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL2825092 1.00 HINT1 (0.68) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL15397114 1.00 HINT1 (0.68) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL28615986 0.93 HINT1 (0.64) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL28981039 0.91 HINT1 (0.57) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL3970953 0.88 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL3514472 0.88 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
SCHEMBL17355882 0.88 HINT1 (0.73) HINT1NT5EGSK3ARPS6KA3MAPK14
Guanosine SCHEMBL28005790 0.87 HPGD (0.66) HINT1NT5EGSK3ARPS6KA3MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180120231-A1 OPTICAL METHOD FOR DETECTING VIABLE CELLS IN A CELL SAMPLE REAMETRIX INC. 2018-05-03 US disclosed
US-9709500-B2 Optical method for detecting viable microorganisms in a cell sample CHARLES RIVER LABORATORIES, INC. (US) 2017-07-18 US disclosed
US-20150368690-A1 VIABILITY STAINING METHOD JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2015-12-24 US disclosed