SCHEMBL17357741

SCHEMBL17357741

CC1=NN(c2ccccc2)C(=O)C1Cc1ccc(N(C)C)cc1

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 16/20 0.78
KDM4E B2RXH2 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
KMT2A Q03164 1/20 0.56
LOX P28300 1/20 0.50
LOXL3 P58215 1/20 0.50
LOXL4 Q96JB6 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
RAB9A P51151 1/20 0.50
ALDH1A1 P00352 1/20 0.48
GFER P55789 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19499378 0.88 CES2 (0.89) CES2KDM4EL3MBTL1MEN1KMT2A
SCHEMBL13104005 0.88 CES2 (1.00) CES2KDM4EL3MBTL1LOXLOXL3
SCHEMBL13851233 0.83 CES2 (0.54) CES2KDM4EL3MBTL1MEN1MAPT
SCHEMBL19506499 0.82 CES2 (0.78) CES2KDM4EL3MBTL1MEN1KMT2A
SCHEMBL4059748 0.79 CES2 (0.82) CES2KDM4EL3MBTL1LOXLOXL3
SCHEMBL13206431 0.78 CES2 (0.54) CES2L3MBTL1MEN1MAPTTHRB
SCHEMBL4240299 0.76 CES2 (0.76) CES2KDM4EL3MBTL1KMT2ALOX
SCHEMBL4663223 0.74 CES2 (0.68) CES2MAPTLOXLOXL3LOXL4
SCHEMBL11869195 0.73 CES2 (0.63) CES2MAPTLOXLOXL3LOXL4
SCHEMBL419526 0.73 CES2 (0.68) CES2KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9481192-B2 Thermal transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2016-11-01 US disclosed
US-9481192-B2 Thermal transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2016-11-01 US disclosed
US-20150367665-A1 THERMAL TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2015-12-24 US disclosed
US-20150367665-A1 THERMAL TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2015-12-24 US disclosed