⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603440 | 0.69 | — | — | |
| SCHEMBL1712110 | 0.68 | — | — | |
| SCHEMBL16050877 | 0.67 | — | — | |
| SCHEMBL2520858 | 0.65 | — | — | |
| SCHEMBL1712963 | 0.65 | — | — | |
| SCHEMBL9443043 | 0.63 | — | — | |
| SCHEMBL6630589 | 0.60 | — | — | |
| SCHEMBL4350685 | 0.56 | — | — | |
| SCHEMBL5329145 | 0.54 | — | — | |
| Isopropyl Alcohol SCHEMBL1236799 | 0.51 | ALDH1A1 (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102669-B2 | Substituted piperidinyl-pyridazinyl derivatives useful as SCD 1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-08-11 | — | — | US | claimed |
| US-20140371220-A1 | SUBSTITUTED PIPERIDINYL-PYRIDAZINYL DERIVATIVES USEFUL AS SCD 1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-18 | — | — | US | claimed |
| WO-2013085957-A1 | SUBSTITUTED PIPERIDINYL-PYRIDAZINYL DERIVATIVES USEFUL AS SCD 1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-06-13 | — | — | WO | claimed |
| US-20240156792-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-05-16 | — | — | US | disclosed |
| US-11918562-B2 | Combination therapy using azabicyclo compound for cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-03-05 | — | — | US | disclosed |
| US-20220016090-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2022-01-20 | — | — | US | disclosed |
| US-11166943-B2 | Combination therapy using azabicyclo compound for cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-11-09 | — | — | US | disclosed |
| US-10849886-B2 | Combination therapy using azabicyclo compound for cancer | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20200281904-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR DISEASES INVOLVING IDO EXPRESSION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-09-10 | — | — | US | disclosed |
| US-20200276171-A1 | COMBINATION THERAPY USING AZABICYCLO COMPOUND FOR CANCER | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-09-03 | — | — | US | disclosed |
| EP-3682900-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR DISEASES INVOLVING IDO EXPRESSION | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-07-22 | — | — | EP | disclosed |
| EP-1931676-B1 | Pyrazolopyrimidines as protein kinase inhibitors | SCHERING CORP (US) | 2011-11-16 | — | — | EP | disclosed |
| US-7776865-B2 | Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors | SCHERING CORPORATION (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100125068-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION | 2010-05-20 | — | — | US | disclosed |
| EP-1942900-A2 | USE OF PYRAZOLO [1,5-A] PYRIMIDINE DERIVATIVES FOR INHIBITING KINASES METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1931676-A1 | PYRAZOLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007044441-A2 | USE OF PYRAZOLO [1 , 5 -A] PYRIMIDINE DERIVATIVES FOR INHIBITING PROTEIN KINASES METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070082900-A1 | Methods for inhibiting protein kinases | SCHERING CORPORATION | 2007-04-12 | — | — | US | disclosed |
| US-20070083044-A1 | Pyrazolopyrimidines as protein kinase inhibitors | SCHERING CORPORATION | 2007-04-12 | — | — | US | disclosed |
| WO-2007041712-A1 | PYRAZOLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |