SCHEMBL17358741

SCHEMBL17358741

CC1C(=O)N(Cc2ccccc2)C(=O)N(Cc2ccccc2)C1=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.67
F2 P00734 1/20 0.67
PLG P00747 1/20 0.67
CTSG P08311 1/20 0.67
CMA1 P23946 1/20 0.67
CTRC Q99895 1/20 0.67
EP300 Q09472 2/20 0.66
KMT2A Q03164 4/20 0.56
MEN1 O00255 2/20 0.56
NPSR1 Q6W5P4 1/20 0.54
GSK3A P49840 1/20 0.52
GSK3B P49841 1/20 0.52
MGLL Q99685 1/20 0.52
EHMT2 Q96KQ7 1/20 0.52
ALDH1A1 P00352 3/20 0.51
ADORA2A P29274 1/20 0.49
TSHR P16473 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10159083 0.81 KMT2A (0.59) ELANEF2PLGCTSGCMA1
SCHEMBL19923759 0.80 SMO (0.60) ELANEF2PLGCTSGCMA1
SCHEMBL10031595 0.80 KMT2A (0.66) ELANEF2PLGCTSGCMA1
SCHEMBL9975770 0.80 KMT2A (0.66) ELANEF2PLGCTSGCMA1
SCHEMBL15131570 0.79 EP300 (1.00) ELANEF2PLGCTSGCMA1
SCHEMBL15131561 0.79 ELANE (0.64) ELANEF2PLGCTSGCMA1
SCHEMBL5252516 0.79 MEN1 (0.53) ELANEF2PLGCTSGCMA1
SCHEMBL6825068 0.79 CACNA1G (0.55) ELANEF2PLGCTSGCMA1
SCHEMBL11375405 0.79 EP300 (0.69) ELANEF2PLGCTSGCMA1
SCHEMBL13793073 0.77 ELANE (0.82) ELANEF2PLGCTSGCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed