Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736539 | 0.99 | DYRK1A (0.47) | DYRK1AMAPTRECQLFABP4CYP19A1 | |
| SCHEMBL1737080 | 0.92 | DYRK1A (0.48) | DYRK1AMAPTFABP4CYP19A1L3MBTL1 | |
| SCHEMBL1736377 | 0.91 | MAPT (0.41) | DYRK1AMAPTADAMTS5KDM4ETP53 | |
| SCHEMBL1737387 | 0.91 | MAPT (0.41) | DYRK1AMAPTADAMTS5KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL1735387 | 0.91 | DYRK1A (0.47) | DYRK1AMAPTFABP4CYP19A1L3MBTL1 | |
| SCHEMBL1735940 | 0.91 | DYRK1A (0.47) | DYRK1AMAPTFABP4CYP19A1L3MBTL1 | |
| SCHEMBL1738711 | 0.90 | MAPT (0.41) | DYRK1AMAPTADAMTS5KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL1737634 | 0.90 | MAPT (0.40) | DYRK1AMAPTADAMTS5KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL1737746 | 0.90 | MAPT (0.40) | DYRK1AMAPTADAMTS5KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL1736586 | 0.90 | DYRK1A (0.47) | DYRK1AMAPTFABP4CYP19A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |