Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737387 | 1.00 | MAPT (0.41) | MAPTTP53HRH3DYRK1AGAA | |
| Hydrochloric Acid SCHEMBL1737746 | 0.99 | MAPT (0.40) | MAPTTP53HRH3DYRK1AGAA | |
| Hydrochloric Acid SCHEMBL1737634 | 0.99 | MAPT (0.40) | MAPTTP53HRH3DYRK1AGAA | |
| SCHEMBL1737594 | 0.95 | HRH3 (0.41) | MAPTTP53HRH3DYRK1AGAA | |
| Hydrochloric Acid SCHEMBL1735552 | 0.94 | HRH3 (0.40) | MAPTTP53HRH3DYRK1AGAA | |
| SCHEMBL1738711 | 0.92 | MAPT (0.41) | MAPTTP53DYRK1AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL1736702 | 0.91 | MAPT (0.40) | MAPTTP53DYRK1AADAMTS5MCL1 | |
| SCHEMBL1735942 | 0.91 | DYRK1A (0.47) | MAPTTP53DYRK1AGAANPSR1 | |
| SCHEMBL1737416 | 0.91 | MAPT (0.41) | MAPTTP53HRH3DYRK1AGAA | |
| SCHEMBL1738968 | 0.91 | MAPT (0.41) | MAPTTP53HRH3DYRK1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |