SCHEMBL17359573

SCHEMBL17359573

COc1cccc(N2N=C(C)/C(=C/C3C(=O)N(c4cccc(OC)c4)N=C3C)C2=O)c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 11/20 0.54
▸ MEN1 O00255 9/20 0.54
▸ MAPT P10636 5/20 0.49
▸ ALDH1A1 P00352 2/20 0.48
▸ GFER P55789 1/20 0.48
▸ GAA P10253 2/20 0.46
▸ AMY1A P0DUB6 4/20 0.46
▸ PSMD14 O00487 2/20 0.44
▸ POLB P06746 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.42
▸ NSD2 O96028 1/20 0.42
▸ DNMT1 P26358 1/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.42
▸ MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17357749 0.91 KMT2A (0.47) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL17342935 0.87 MAPT (0.63) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL10078302 0.84 MAPT (0.61) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL247053 0.84 MAPT (0.61) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL305089 0.84 MAPT (0.61) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL17342938 0.80 MAPT (0.53) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL14488588 0.76 MAPT (0.52) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL9788461 0.74 KAT8 (0.55) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL9296161 0.74 KAT8 (0.55) KMT2AMEN1MAPTALDH1A1GFER
SCHEMBL28476777 0.73 KMT2A (0.73) KMT2AMEN1MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647142-B2 Thermal transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2020-05-12 — — US disclosed
US-20180170085-A1 THERMAL TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2018-06-21 — — US disclosed
US-9481192-B2 Thermal transfer recording sheet CANON KABUSHIKI KAISHA (JP) 2016-11-01 — — US disclosed
US-20150367665-A1 THERMAL TRANSFER RECORDING SHEET CANON KABUSHIKI KAISHA (JP) 2015-12-24 — — US disclosed
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