Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1735619 | 0.99 | KDM4E (0.43) | KDM4EALDH1A1CYP1A2CYP2C19TSHR | |
| SCHEMBL1737115 | 0.83 | MEN1 (0.41) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1737696 | 0.83 | FABP4 (0.50) | KDM4EALDH1A1CYP1A2CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL1735614 | 0.82 | MEN1 (0.43) | KDM4EALDH1A1MEN1KMT2AMCL1 | |
| Hydrochloric Acid SCHEMBL1735464 | 0.82 | FABP4 (0.49) | KDM4EALDH1A1CYP1A2CYP2C19TSHR | |
| SCHEMBL1737421 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1739779 | 0.81 | MEN1 (0.50) | ALDH1A1CYP1A2CYP2C19TSHRCYP2C9 | |
| Hydrochloric Acid SCHEMBL1738010 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1736472 | 0.80 | MEN1 (0.49) | KDM4EALDH1A1CYP1A2CYP2C19TSHR | |
| SCHEMBL1738218 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | disclosed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |