SCHEMBL1735988

SCHEMBL1735988

CC(=O)CC(=O)n1cnc2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 6/20 0.55
SMN1; SMN2 Q16637 3/20 0.52
NPC1 O15118 2/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
RAB9A P51151 1/20 0.51
HSD17B10 Q99714 1/20 0.51
KMT2A Q03164 3/20 0.50
MEN1 O00255 1/20 0.50
HTT P42858 1/20 0.48
LMNA P02545 1/20 0.47
STAT6 P42226 1/20 0.47
KDM4E B2RXH2 1/20 0.47
DNMT3A Q9Y6K1 1/20 0.46
APAF1 O14727 1/20 0.46
EGLN3 Q9H6Z9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11012986 0.83 NPC1 (0.57) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL7132708 0.81 ASAH1 (0.55) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL3078847 0.81 SMN1; SMN2 (0.59) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL24110360 0.79 SMN1; SMN2 (0.58) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL32660141 0.79 ASAH1 (0.52) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL593554 0.78 KMT2A (0.48) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL7790594 0.77 ASAH1 (0.51) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL11443588 0.77 KMT2A (0.60) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL250172 0.77 HTT (0.66) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL9791225 0.77 KMT2A (0.60) ASAH1SMN1; SMN2NPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146094-B1 Water-based pigment dispersion, use thereof and process for the production thereof TOYO INK MFG CO (JP) 2011-11-16 EP disclosed
US-20110261706-A1 COMMUNICATION APPARATUS AND COMMUNICATION METHOD PANASONIC CORPORATION (JP) 2011-10-27 US disclosed
US-6648954-B2 Pigment, sulfonic acid group-containing pigment derivative and water; inkjet recording liquid TOYO INK MFG. CO., LTD. (JP) 2003-11-18 US disclosed
US-20010029870-A1 Water-based pigment dispersion, use thereof and process for the production thereof TOYO INK MFG. CO., LTD. (JP) 2001-10-18 US disclosed
EP-1146094-A2 Water-based pigment dispersion, use thereof and process for the production thereof TOYO INK MANUFACTURING CO., LTD. (JP) 2001-10-17 EP disclosed