SCHEMBL3078847

SCHEMBL3078847

CC(=O)n1cnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ KMT2A Q03164 3/20 0.57
▸ MEN1 O00255 1/20 0.56
▸ LMNA P02545 1/20 0.54
▸ STAT6 P42226 1/20 0.54
▸ ASAH1 Q13510 6/20 0.54
▸ HTT P42858 1/20 0.54
▸ NPC1 O15118 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ RAB9A P51151 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ DNMT3A Q9Y6K1 1/20 0.51
▸ APAF1 O14727 1/20 0.47
▸ EGLN3 Q9H6Z9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443588 0.84 KMT2A (0.60) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL250172 0.84 HTT (0.66) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL857765 0.82 SMN1; SMN2 (0.61) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL5348211 0.82 SMN1; SMN2 (0.54) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL8818598 0.82 KMT2A (0.54) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL1735988 0.81 ASAH1 (0.55) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL29585279 0.81 SMN1; SMN2 (0.54) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL28377896 0.81 SMN1; SMN2 (0.54) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL11882632 0.81 KMT2A (0.57) SMN1; SMN2KMT2AMEN1LMNASTAT6
SCHEMBL5133119 0.81 KMT2A (0.57) SMN1; SMN2KMT2AMEN1LMNASTAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 — — US claimed
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease UNIVERSITE DE MONTREAL (CA) 2025-11-25 — — US disclosed
US-20250270207-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE UNIVERSITE DE MONTREAL (CA) 2025-08-28 — — US disclosed
US-12139488-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease Université de Montréal (CA) 2024-11-12 — — US disclosed
US-20240317747-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE Université de Montréal (CA) 2024-09-26 — — US disclosed
US-12060353-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease Université de Montréal (CA) 2024-08-13 — — US disclosed
US-20240217971-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE Université de Montréal (CA) 2024-07-04 — — US disclosed
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-05-30 — — US disclosed
US-20240140945-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE Université de Montréal (CA) 2024-05-02 — — US disclosed
EP-4347544-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES Dow Technology Investments LLC (US) 2024-04-10 — — EP disclosed
EP-0063017-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-20 — — EP disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 — — EP disclosed
EP-0057088-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-08-04 — — EP disclosed
EP-0051987-A1 Bleach activator compositions, preparation thereof and use in granular detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 — — EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 — — US disclosed
EP-0034387-A2 Mulls containing chain structure clay suspension aids THE PROCTER & GAMBLE COMPANY (US) 1981-08-26 — — EP disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 — — EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 — — US disclosed
US-4248928-A TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 — — US disclosed
US-4179390-A Laundry additive product THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270207-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, KRAS SMN1; SMN2 3085/4885KMT2A 2292/4885MEN1 1789/4885
US-20240140945-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, KRAS SMN1; SMN2 3085/4885KMT2A 2292/4885MEN1 1789/4885
US-20240317747-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, KRAS SMN1; SMN2 3085/4885KMT2A 2292/4885MEN1 1789/4885
US-12139488-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, KRAS SMN1; SMN2 3085/4885KMT2A 2292/4885MEN1 1789/4885
US-12060353-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, KRAS SMN1; SMN2 3085/4885KMT2A 2292/4885MEN1 1789/4885
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, DPYD SMN1; SMN2 3097/4885KMT2A 2305/4885MEN1 1888/4885
US-20240217971-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, DPYD SMN1; SMN2 3097/4885KMT2A 2305/4885MEN1 1888/4885
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES ADH1C, ADH5, ALDH2 SMN1; SMN2 1192/4885KMT2A 191/4885MEN1 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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