SCHEMBL1735989

SCHEMBL1735989

CC(=O)CC(=O)c1nc2ccccc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
DAGLA Q9Y4D2 2/20 0.55
LMNA P02545 2/20 0.54
XDH P47989 2/20 0.52
AURKA O14965 1/20 0.51
JAK2 O60674 1/20 0.51
ABL1 P00519 1/20 0.51
NTRK1 P04629 1/20 0.51
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
CSF1R P07333 1/20 0.51
RET P07949 1/20 0.51
IGF1R P08069 1/20 0.51
MET P08581 1/20 0.51
PDGFRB P09619 1/20 0.51
PIM1 P11309 1/20 0.51
FGFR1 P11362 1/20 0.51
PRKACA P17612 1/20 0.51
KDR P35968 1/20 0.51
MAP2K2 P36507 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1901781 0.83 SMN1; SMN2 (0.61) MAPTDAGLALMNAXDHAURKA
SCHEMBL30831206 0.83 SMN1; SMN2 (0.61) MAPTDAGLALMNAXDHAURKA
SCHEMBL27203418 0.83 DAGLA (0.57) MAPTDAGLALMNAXDHAURKA
SCHEMBL1132610 0.81 MAPT (0.62) MAPTDAGLALMNAXDHAURKA
SCHEMBL29493675 0.80 DAGLA (0.57) MAPTDAGLALMNAXDHAURKA
SCHEMBL6039391 0.80 DAGLA (0.57) MAPTDAGLALMNAXDHAURKA
SCHEMBL28491473 0.80 XDH (0.62) MAPTDAGLALMNAXDHAURKA
SCHEMBL29414979 0.80 XDH (0.62) MAPTDAGLALMNAXDHAURKA
Chloromethane SCHEMBL29246404 0.80 MAPT (0.60) MAPTLMNAXDHAURKAJAK2
SCHEMBL10464100 0.79 DAGLA (0.64) MAPTDAGLALMNAXDHAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146094-B1 Water-based pigment dispersion, use thereof and process for the production thereof TOYO INK MFG CO (JP) 2011-11-16 EP disclosed
US-20110261706-A1 COMMUNICATION APPARATUS AND COMMUNICATION METHOD PANASONIC CORPORATION (JP) 2011-10-27 US disclosed
US-6648954-B2 Pigment, sulfonic acid group-containing pigment derivative and water; inkjet recording liquid TOYO INK MFG. CO., LTD. (JP) 2003-11-18 US disclosed
US-20010029870-A1 Water-based pigment dispersion, use thereof and process for the production thereof TOYO INK MFG. CO., LTD. (JP) 2001-10-18 US disclosed
EP-1146094-A2 Water-based pigment dispersion, use thereof and process for the production thereof TOYO INK MANUFACTURING CO., LTD. (JP) 2001-10-17 EP disclosed
EP-0210284-B1 1,3-DITHIOL-2-YLIDENE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-08-19 EP disclosed
US-4668799-A Anti-hepatitis and anti-cirrhotic 1,3-dithiol-2-ylidene derivatives, and pharmaceutical compositions therefor BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-05-26 US disclosed
EP-0210284-A1 1,3-Dithiol-2-ylidene derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-02-04 EP disclosed