Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.57 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nervonic Acid SCHEMBL20694895 | 1.00 | EPHX2 (0.57) | EPHX2TERTPTPN1PPARGPPARD | |
| Oleic Acid SCHEMBL1287108 | 1.00 | EPHX2 (0.57) | EPHX2TERTPTPN1PPARGPPARD | |
| Linoleic Acid SCHEMBL3357717 | 0.97 | KDM4E (0.59) | EPHX2PPARGPPARDPPARAMAPT | |
| Linoleic Acid SCHEMBL3357720 | 0.97 | KDM4E (0.59) | EPHX2PPARGPPARDPPARAMAPT | |
| Arachidonic Acid SCHEMBL5807411 | 0.93 | MEN1 (0.58) | EPHX2PPARGPPARDPPARAMAPT | |
| Arachidonic Acid SCHEMBL5807415 | 0.93 | MEN1 (0.58) | EPHX2PPARGPPARDPPARAMAPT | |
| Arginine SCHEMBL1690131 | 0.93 | NOD1 (0.54) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| Decanoic Acid SCHEMBL6040143 | 0.93 | NOD1 (0.54) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| Palmitic Acid SCHEMBL1287143 | 0.93 | NOD1 (0.54) | PTPN1PPARGPPARDPPARAHSD17B10 | |
| Decanoic Acid SCHEMBL11052064 | 0.93 | NOD1 (0.54) | PTPN1PPARGPPARDPPARAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118576561-A | Method for optimizing biocompatible vesicle-coated sinomenine hydrochloride by response surface method | 中国农业大学 | 2024-09-03 | — | — | CN | disclosed |
| EP-2399885-A1 | Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification | Dietz, Ulrich (DE) | 2011-12-28 | — | — | EP | disclosed |
| EP-0964673-B1 | PROTECTIVE AGENTS FOR SKIN AND HAIR | TAKASAGO PERFUMERY CO LTD (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6355232-B1 | CERAMIDE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0964673-A4 | PROTECTIVE AGENTS FOR SKIN AND HAIR | TAKASAGO PERFUMERY CO LTD (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-0964673-A1 | PROTECTIVE AGENTS FOR SKIN AND HAIR | Takasago International Corporation (JP) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998027958-A1 | PROTECTIVE AGENTS FOR SKIN AND HAIR | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-07-02 | — | — | WO | disclosed |