SCHEMBL17360510

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17532997	0.83	NTRK1 (0.51)	NTRK1MAP4K4MEN1KMT2A
	SCHEMBL623961	0.82	MAP4K4 (0.57)	NTRK1MAP4K4CYP1A2KCNH2MINK1
	SCHEMBL625203	0.80	MAP4K4 (0.50)	NTRK1MAP4K4CYP1A2KCNH2MINK1
	SCHEMBL17360450	0.78	NTRK1 (0.73)	NTRK1
	SCHEMBL17360475	0.78	NTRK1 (0.73)	NTRK1
	SCHEMBL6509007	0.78	NPSR1 (0.57)	NPSR1CYP1A2KCNH2MEN1NPC1
	SCHEMBL17360185	0.77	NTRK1 (0.80)	NTRK1
	SCHEMBL17360302	0.77	NTRK1 (0.73)	NTRK1
	SCHEMBL17360092	0.77	NTRK1 (0.71)	NTRK1
	SCHEMBL870523	0.75	BTK (0.51)	NTRK1MAP4K4CYP1A2KCNH2MINK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.