Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065223 | 0.84 | MEN1 (0.62) | NPSR1MAOAMAOBMEN1KMT2A | |
| SCHEMBL22534745 | 0.80 | MEN1 (0.62) | MAOBMEN1KMT2AGAARAB9A | |
| SCHEMBL22404982 | 0.80 | NPSR1 (0.57) | NPSR1MAOAMAOBMEN1KMT2A | |
| SCHEMBL16528704 | 0.80 | MAPT (0.57) | NPSR1MAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18956822 | 0.79 | MEN1 (0.55) | MAOAMAOBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18742179 | 0.78 | SCN9A (0.57) | NPSR1MAOAMAOBMEN1KMT2A | |
| SCHEMBL17360510 | 0.78 | NTRK1 (0.55) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4059342 | 0.77 | KDM4E (0.69) | MAOAMAOBMEN1KMT2ARAB9A | |
| SCHEMBL27267264 | 0.77 | MEN1 (0.63) | NPSR1MAOAMAOBMEN1KMT2A | |
| SCHEMBL21902996 | 0.76 | SMN1; SMN2 (0.56) | NPSR1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |