SCHEMBL17360642

SCHEMBL17360642

Cc1c2oc3c(C)c(N)cc(C(=O)NC4C(=O)NC(C(C)C)C(=O)N5CCCC5C(=O)N(C)CC(=O)N(C)C(C(C)C)C(=O)OC4C)c3nc-2c(C(=O)NC2C(=O)NC(C(C)C)C(=O)N3CCCC3C(=O)N(C)CC(=O)N(C)C(C(C)C)C(=O)OC2C)c(N)c1=O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRB2 P62993 3/20 0.86
MAPT P10636 2/20 0.86
RECQL P46063 2/20 0.86
SMN1; SMN2 Q16637 2/20 0.86
ABCB11 O95342 1/20 0.86
ALDH1A1 P00352 1/20 0.86
CYP3A4 P08684 1/20 0.86
ALOX15 P16050 1/20 0.86
PTGS1 P23219 1/20 0.86
CASP1 P29466 1/20 0.86
HTT P42858 1/20 0.86
BLM P54132 1/20 0.86
CASP7 P55210 1/20 0.86
KMT2A Q03164 1/20 0.86
HIF1A Q16665 1/20 0.86
DDR2 Q16832 1/20 0.86
NGLY1 Q96IV0 1/20 0.86
HSD17B10 Q99714 1/20 0.86
HDAC6 Q9UBN7 2/20 0.30
HDAC3 O15379 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502640 1.00 GRB2 (0.86) GRB2MAPTRECQLSMN1; SMN2ABCB11
SCHEMBL29352907 1.00 GRB2 (0.86) GRB2MAPTRECQLSMN1; SMN2ABCB11
SCHEMBL29352655 1.00 GRB2 (0.86) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL6939686 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL3845 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL13659669 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL19770615 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL6152 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL3844 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11
Dactinomycin SCHEMBL27304406 0.93 GRB2 (1.00) GRB2MAPTRECQLSMN1; SMN2ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-12-25 US disclosed
EP-3256850-B1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES INC (US) 2025-07-09 EP disclosed
US-12352679-B2 Synthetic human cell mimic particle for cytometric or coulter device SLINGSHOT BIOSCIENCES, INC. (US) 2025-07-08 US disclosed
US-20250189428-A1 COMPOSITIONS AND METHODS FOR SINGLE WELL MULTIPLEXED CALIBRATION AND COMPENSATION SLINGSHOT BIOSCIENCES, INC. (US) 2025-06-12 US disclosed
US-20250164373-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-22 US disclosed
EP-3864140-B1 ANALYSIS OF VIABLE AND NONVIABLE CELLS SAGEMEDIC CORP (US) 2025-05-21 EP disclosed
US-20250093251-A1 SIZE-TUNABLE SYNTHETIC PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME IMMUNE CELL ACTIVATION SLINGSHOT BIOSCIENCES, INC. 2025-03-20 US disclosed
US-12196661-B2 Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation SLINGSHOT BIOSCIENCES, INC. (US) 2025-01-14 US disclosed
US-20240353305-A1 SIZE-TUNABLE SYNTHETIC PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME FOR IMMUNE CELL ACTIVATION SLINGSHOT BIOSCIENCES, INC. 2024-10-24 US disclosed
US-12066369-B2 Synthetic human cell mimic particle for cytometric or coulter device SLINGSHOT BIOSCIENCES, INC. (US) 2024-08-20 US disclosed
US-20180275040-A1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES, INC. (US) 2018-09-27 US disclosed
EP-3256850-A1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME Slingshot Biosciences, Inc. (US) 2017-12-20 EP disclosed
US-9714897-B2 Hydrogel particles with tunable optical properties and methods for using the same SLINGSHOT BIOSCIENCES, INC. (US) 2017-07-25 US disclosed
US-20170143735-A1 METHODS FOR TREATING, DIAGNOSING AND PROGNOSING A HAEMATOLOGICAL MALIGNANCY INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS (ES) 2017-05-25 US disclosed
EP-3160472-A1 METHODS FOR TREATING, DIAGNOSING AND PROGNOSING A HAEMATOLOGICAL MALIGNANCY Institut De Recerca Contra La Leucemia Josep Carreras (ES) 2017-05-03 EP disclosed
CN-106471373-A For treat, diagnose and prognosis Malignancy method 约瑟卡雷拉斯白血球过多症研究所 2017-03-01 CN disclosed
US-20160258856-A1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES, INC. 2016-09-08 US disclosed
WO-2016130489-A1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES, INC. (US) 2016-08-18 WO disclosed
EP-2959904-A1 Methods for treating, diagnosing and prognosing a haematological malignancy Institut De Recerca Contra La Leucemia Josep Carreras (ES) 2015-12-30 EP disclosed
WO-2015197839-A1 METHODS FOR TREATING, DIAGNOSING AND PROGNOSING A HAEMATOLOGICAL MALIGNANCY INSTITUT DE RECERCA CONTRA LA LEUCÈMIA JOSEP CARRERAS (ES) 2015-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE CD4, ICOS, CD69 GRB2 1405/4885MAPT 1949/4885RECQL 3502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.