SCHEMBL173641

SCHEMBL173641

FC(F)(F)c1ccncc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.70
ALDH1A1 P00352 1/20 0.53
TSHR P16473 1/20 0.53
USP2 O75604 1/20 0.48
RAB9A P51151 1/20 0.48
NOS3 P29474 1/20 0.48
NOS2 P35228 1/20 0.48
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
S1PR1 P21453 1/20 0.42
S1PR3 Q99500 1/20 0.42
CYP19A1 P11511 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ORAI1 Q96D31 1/20 0.42
ORAI2 Q96SN7 1/20 0.42
ORAI3 Q9BRQ5 1/20 0.42
TRPV6 Q9H1D0 1/20 0.42
MGLL Q99685 1/20 0.42
NISCH Q9Y2I1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28086851 0.97 KIF11 (0.67) KIF11ALDH1A1TSHRUSP2RAB9A
Hydrochloric Acid SCHEMBL7816092 0.97 KIF11 (0.67) KIF11ALDH1A1TSHRUSP2RAB9A
Bromide SCHEMBL28026302 0.97 KIF11 (0.67) KIF11ALDH1A1TSHRUSP2RAB9A
Fluoride SCHEMBL17966118 0.94 KIF11 (0.64) KIF11ALDH1A1TSHRUSP2RAB9A
Cyclohexane SCHEMBL28283907 0.91 KIF11 (0.61) KIF11ALDH1A1TSHRUSP2RAB9A
SCHEMBL17966120 0.91 KIF11 (0.61) KIF11ALDH1A1TSHRUSP2RAB9A
SCHEMBL21490758 0.89 KIF11 (0.58) KIF11ALDH1A1TSHRUSP2RAB9A
SCHEMBL9952289 0.89 KIF11 (0.65) KIF11ALDH1A1TSHRUSP2RAB9A
SCHEMBL31247752 0.84 KIF11 (0.54) KIF11ALDH1A1TSHRUSP2RAB9A
SCHEMBL29091784 0.84 KIF11 (0.54) KIF11USP2RAB9ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 973 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122636-A1 METHOD FOR THE SYNTHESIS OF ACRYLATE DERIVATIVES Orthobond Corporation (US) 2025-06-12 WO claimed
CN-119638619-A Indan pyridine amide compound and preparation method and application thereof 盐城工学院 2025-03-18 CN claimed
CN-119630645-A Flavivirus inhibitors IRBM股份公司 2025-03-14 CN claimed
CN-115448940-B Preparation method of chiral gem diaryl methylene silane compound 苏州凯若利新材料科技有限公司 2025-03-04 CN claimed
CN-119176800-A Pyridine thiophene acetamide compound and preparation method and application thereof 盐城工学院 2024-12-24 CN claimed
CN-118880406-A Corrosion-resistant aluminum coating with preferred orientation of (200) on magnesium alloy surface and preparation method thereof 三磊(宁波)新材料科技有限公司 2024-11-01 CN claimed
CN-117430544-A Method for preparing isoindoline compound by taking alpha-amino acetal as substrate 南京工业大学 2024-01-23 CN claimed
EP-4289271-A2 METHOD AND POLYMERIC MATERIAL HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST MOSQUITOES SYNGENTA PARTICIPATIONS AG (CH) 2023-12-13 EP claimed
CN-117165078-A Cyanate resin with low dielectric loss suitable for winding forming process, preparation method and application 中国科学院宁波材料技术与工程研究所 2023-12-05 CN claimed
CN-117050009-A Preparation method of 4-trifluoromethyl pyridine intermediate core parent nucleus and derivatives thereof 台州臻挚生物科技有限公司 2023-11-14 CN claimed
EP-0791034-B1 METHINE AND AZAMETHINE DYES MADE FROM TRIFLUOROMETHYLPYRIDONES BASF AG (DE) 2002-01-09 EP claimed
CN-1274528-A N-(heterocycloformyl) sulfonamide herbicide SHENYANG INST OF CHEMICAL ENGI (CN) 2000-11-29 CN claimed
CN-1255042-A Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them ISK AMERICAS INC (US) 2000-05-31 CN claimed
US-4563529-A VAPOR PHASE CATALYTIC FLUORINATION OF PICOLINES OR LUTIDINES ISHIHARA SANGYO KAISHA LTD. (JP) 1986-01-07 US claimed
US-4514565-A Thiazolylacetamido cephalosphorin compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-04-30 US claimed
EP-0042696-B1 PROCESS FOR PRODUCING TRIFLUOROMETHYLPYRIDINES ISHIHARA SANGYO KAISHA LTD. (JP) 1983-11-16 EP claimed
EP-0042696-A1 Process for producing trifluoromethylpyridines ISHIHARA SANGYO KAISHA LTD. (JP) 1981-12-30 EP claimed
US-4296111-A 7-Substituted methyl cephalosporins derivatives and analogues thereof MERCK & CO. INC. (US) 1981-10-20 US claimed
US-4132789-A 7-[2-(2-Imino-4-thiazolin-4-yl)-2-sulfoacetamido]cephalosporins and antibacterial compositions containing them TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-01-02 US claimed
US-4032521-A ANTIBIOTICS MERCK & CO., INC. (US) 1977-06-28 US claimed