Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 16/20 | 0.54 |
| ▸ | WNT1 | P04628 | 11/20 | 0.52 |
| ▸ | CLK2 | P49760 | 9/20 | 0.51 |
| ▸ | CLK3 | P49761 | 9/20 | 0.51 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14792936 | 0.88 | DYRK1A (0.63) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL14792111 | 0.85 | WNT1 (0.55) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL14792142 | 0.85 | WNT1 (0.60) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14804255 | 0.84 | WNT1 (0.57) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL18160631 | 0.84 | DYRK1A (0.58) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL14792717 | 0.84 | WNT1 (0.70) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792636 | 0.84 | DYRK1A (0.66) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL14792731 | 0.83 | DYRK1A (0.58) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14785617 | 0.82 | DYRK1A (0.63) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792110 | 0.82 | WNT1 (0.61) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221793-B2 | Indazole-3-carboxamides and their use as Wnt/β-catenin signaling pathway inhibitors | SAMUMED, LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221793-B2 | Indazole-3-carboxamides and their use as Wnt/β-catenin signaling pathway inhibitors | SAMUMED, LLC (US) | 2015-12-29 | — | — | US | disclosed |