Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364531 | 0.91 | RORC (0.53) | RORC | |
| SCHEMBL17365398 | 0.86 | RORC (0.51) | RORC | |
| SCHEMBL16632674 | 0.79 | RORC (0.72) | RORC | |
| SCHEMBL16633045 | 0.78 | RORC (0.73) | RORC | |
| SCHEMBL21538898 | 0.73 | RORC (0.47) | RORC | |
| SCHEMBL21574708 | 0.73 | RORC (0.59) | RORC | |
| SCHEMBL16632620 | 0.72 | RORC (0.64) | RORC | |
| SCHEMBL15648578 | 0.72 | RORC (0.55) | RORC | |
| SCHEMBL16479496 | 0.72 | RORC (0.72) | RORC | |
| SCHEMBL16460660 | 0.70 | RORC (0.69) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |