Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 14/20 | 0.59 |
| ▸ | KDM5C | P41229 | 8/20 | 0.59 |
| ▸ | KDM5A | P29375 | 7/20 | 0.59 |
| ▸ | KDM4A | O75164 | 2/20 | 0.59 |
| ▸ | KDM6B | O15054 | 1/20 | 0.59 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.58 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15994219 | 0.91 | KDM5B (0.61) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL15994214 | 0.83 | KDM5B (0.72) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364570 | 0.82 | KDM5B (0.51) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL16293466 | 0.81 | KDM5B (0.59) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364567 | 0.78 | KDM5B (0.44) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL19676485 | 0.77 | KDM5B (0.55) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364564 | 0.77 | KDM5B (0.63) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL15996136 | 0.76 | KDM5B (0.62) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL15996137 | 0.76 | KDM5B (0.62) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364565 | 0.76 | KDM5B (0.75) | KDM5BKDM5CKDM5AKDM4AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221801-B2 | Inhibitors of histone demethylases | EPITHERAPEUTICS APS (DK) | 2015-12-29 | — | — | US | disclosed |