Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 13/20 | 0.44 |
| ▸ | KDM5C | P41229 | 8/20 | 0.44 |
| ▸ | KDM5A | P29375 | 7/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16293695 | 0.93 | KDM5B (0.46) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364563 | 0.88 | KDM5B (0.42) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL16303323 | 0.86 | KDM5B (0.41) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL16293261 | 0.86 | KDM5B (0.41) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364568 | 0.78 | KDM5B (0.59) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364570 | 0.75 | KDM5B (0.51) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL16293466 | 0.74 | KDM5B (0.59) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL20041897 | 0.72 | KDM5B (0.43) | KDM5BKDM5CKDM5AKDM4AKDM6B | |
| SCHEMBL17364569 | 0.71 | KDM4E (0.42) | KDM5B | |
| SCHEMBL15994214 | 0.70 | KDM5B (0.72) | KDM5BKDM5CKDM5AKDM4AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221801-B2 | Inhibitors of histone demethylases | EPITHERAPEUTICS APS (DK) | 2015-12-29 | — | — | US | disclosed |