Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 6/20 | 0.44 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020785 | 0.86 | XIAP (0.42) | NMUR2NMUR1CALCRLPRMT5WDR77 | |
| SCHEMBL9068934 | 0.83 | CALCRL (0.52) | NMUR2CALCRLPRMT5WDR77CAPN1 | |
| SCHEMBL16018483 | 0.83 | XIAP (0.42) | NMUR2NMUR1CALCRLPRMT5WDR77 | |
| SCHEMBL9082723 | 0.83 | CALCRL (0.55) | NMUR2CALCRLPRMT5WDR77CAPN1 | |
| SCHEMBL31497340 | 0.81 | KEAP1 (0.54) | NMUR2NMUR1CALCRLPRMT5WDR77 | |
| SCHEMBL31497328 | 0.81 | KEAP1 (0.52) | NMUR2CALCRLPRMT5WDR77CAPN1 | |
| SCHEMBL6524705 | 0.80 | BACE1 (0.48) | NMUR2CALCRLREN | |
| SCHEMBL31497335 | 0.79 | KEAP1 (0.55) | NMUR2CALCRLPRMT5WDR77CAPN1 | |
| SCHEMBL7401470 | 0.79 | CALCRL (0.48) | CALCRLKEAP1 | |
| SCHEMBL31497348 | 0.78 | CALCRL (0.50) | NMUR2NMUR1CALCRLPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221889-B2 | VEGF-specific capture agents, compositions, and methods of using and making | INDI MOLECULAR, INC. (US) | 2015-12-29 | — | — | US | disclosed |