Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 10/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366185 | 0.90 | CYP2C9 (0.60) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL17366148 | 0.89 | CYP2C9 (0.57) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL17366155 | 0.88 | CYP2C9 (0.56) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL12332978 | 0.83 | MDM2 (0.53) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL17366178 | 0.83 | MDM2 (0.56) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL31667491 | 0.79 | CYP2C9 (0.65) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL17366195 | 0.77 | CYP2C9 (0.52) | CYP2C9CYP2C19MEN1KMT2AMDM2 | |
| SCHEMBL30121977 | 0.77 | MDM2 (0.64) | MEN1KMT2AMDM2CA12CA1 | |
| SCHEMBL8274847 | 0.75 | MEN1 (0.55) | MEN1KMT2AMDM2GAA | |
| SCHEMBL17366153 | 0.75 | MDM2 (0.52) | CYP2C9CYP2C19MEN1KMT2AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-B1 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECH LTD (GB) | 2019-10-30 | — | — | EP | disclosed |
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |