Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366185 | 0.81 | CYP2C9 (0.60) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL17366148 | 0.80 | CYP2C9 (0.57) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL17366158 | 0.77 | CYP2C9 (0.56) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL17366155 | 0.77 | CYP2C9 (0.56) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL31667491 | 0.75 | CYP2C9 (0.65) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL30121977 | 0.68 | MDM2 (0.64) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL17366153 | 0.67 | MDM2 (0.52) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL12332978 | 0.66 | MDM2 (0.53) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL17366164 | 0.66 | MDM2 (0.53) | CYP2C9CYP2C19MEN1KMT2APOLB | |
| SCHEMBL17366183 | 0.66 | MDM2 (0.53) | CYP2C9CYP2C19MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |