Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 5/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TEC | P42680 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 6/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NCK1 | P16333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483893 | 0.81 | NCF1 (0.68) | NCF1NQO1KDM4EKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27511022 | 0.79 | NCF1 (0.66) | NCF1NQO1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL17430137 | 0.77 | NCF1 (0.49) | NCF1CRHBPCRHR2TECNQO1 | |
| SCHEMBL3976094 | 0.77 | NPC1 (0.46) | NCF1CRHBPCRHR2BACE1 | |
| SCHEMBL28806133 | 0.77 | MAPT (0.46) | NCF1CRHBPCRHR2KMT2AL3MBTL1 | |
| SCHEMBL2323241 | 0.77 | KMT2A (0.54) | NCF1NQO1KDM4EKMT2AALDH1A1 | |
| SCHEMBL22117603 | 0.75 | NCF1 (0.54) | NCF1TECKDM4E | |
| SCHEMBL27929529 | 0.74 | PDE3B (0.51) | NCF1KDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL15451776 | 0.74 | NCF1 (0.55) | NCF1KDM4E | |
| SCHEMBL1598979 | 0.74 | BACE1 (0.39) | NCF1BACE1PLAUNMT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |