Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705834 | 0.86 | ALDH1A1 (0.51) | ALDH1A1GAATP53LMNAMEN1 | |
| SCHEMBL9570228 | 0.83 | ALDH1A1 (0.96) | ALDH1A1GAATP53KDM1AMEN1 | |
| SCHEMBL12441375 | 0.82 | GAA (0.46) | ALDH1A1GAATP53LMNAMEN1 | |
| SCHEMBL9967704 | 0.81 | KDM1A (0.56) | ALDH1A1GAATP53LMNAKDM1A | |
| SCHEMBL8134520 | 0.81 | ALDH1A1 (0.73) | ALDH1A1GAATP53KDM1AMEN1 | |
| SCHEMBL3505965 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAATP53LMNAMEN1 | |
| SCHEMBL4009167 | 0.80 | GAA (0.45) | ALDH1A1GAATP53LMNAMEN1 | |
| SCHEMBL12173077 | 0.80 | NPSR1 (0.48) | ALDH1A1GAATP53LMNAMEN1 | |
| SCHEMBL13499940 | 0.80 | NPSR1 (0.57) | ALDH1A1GAATP53LMNAKDM1A | |
| SCHEMBL5866593 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAATP53LMNAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |