SCHEMBL17366265

SCHEMBL17366265

IN1CCC2(CCCC2)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18389355 0.97 GRM5 (0.34) GRM5HSD11B1
SCHEMBL17461312 0.94
SCHEMBL18938451 0.90 USP2 (0.32)
SCHEMBL23432506 0.86 TSHR (0.32) GRM5
SCHEMBL19979493 0.85
SCHEMBL19046977 0.83 GRM5 (0.31) GRM5
SCHEMBL24919170 0.83
SCHEMBL20778208 0.82
SCHEMBL20778205 0.80 CYP11B1 (0.31)
SCHEMBL16891946 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3919484-B1 HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF SHANDONG XUANZHU PHARMA CO LTD (CN) 2023-05-24 EP disclosed
WO-2022026500-A1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CRPORATION (US) 2022-02-03 WO disclosed
WO-2020216298-A1 HDAC INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF 成都先导药物开发股份有限公司 2020-10-29 WO disclosed
WO-2020205538-A1 CD73 INHIBITORS AND THERAPEUTIC USES THEREOF Eternity Bioscience Inc. (US) 2020-10-08 WO disclosed
EP-3459936-A1 NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT Kemimedi Co. Ltd (KR) 2019-03-27 EP disclosed
WO-2019039818-A1 PYRIMIDINONE DERIVATIVE COMPOUND AND USE THEREOF 보령제약 주식회사 2019-02-28 WO disclosed
WO-2018121678-A1 PRODRUG OF ANTIVIRAL NUCLEOSIDE ANALOGUES, AND COMPOSITION AND USE THEREOF 广东东阳光药业有限公司 2018-07-05 WO disclosed
WO-2017011552-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. (US) 2017-01-19 WO disclosed
EP-2588451-B1 PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS BOEHRINGER INGELHEIM INT (DE) 2015-12-30 EP disclosed