Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17461312 | 0.90 | — | — | |
| SCHEMBL19046977 | 0.90 | GRM5 (0.31) | — | |
| SCHEMBL17366265 | 0.90 | GRM5 (0.31) | — | |
| SCHEMBL24919170 | 0.90 | — | — | |
| SCHEMBL18389355 | 0.87 | GRM5 (0.34) | TSHR | |
| SCHEMBL23432506 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL19979493 | 0.81 | — | — | |
| SCHEMBL15679583 | 0.79 | CYP2D6 (0.47) | USP2CYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL24369038 | 0.79 | USP2 (0.51) | USP2CYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL18995622 | 0.79 | HRH3 (0.35) | USP2CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096045-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |