Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24505633 | 1.00 | CA2 (0.34) | CA2DNM1TSHRSMN1; SMN2FDPS | |
| SCHEMBL9063930 | 0.85 | — | — | |
| SCHEMBL7524174 | 0.85 | CA2 (0.39) | CA2DNM1TSHRSMN1; SMN2FDPS | |
| SCHEMBL16588260 | 0.81 | — | — | |
| SCHEMBL10022171 | 0.80 | — | — | |
| SCHEMBL7529986 | 0.80 | CA2 (0.45) | CA2DNM1FDPSCA1 | |
| SCHEMBL15178203 | 0.80 | CA2 (0.45) | CA2DNM1FDPSCA1 | |
| SCHEMBL17225874 | 0.80 | CA2 (0.37) | CA2DNM1TSHRSMN1; SMN2FDPS | |
| SCHEMBL16315511 | 0.80 | CA2 (0.37) | CA2DNM1TSHRSMN1; SMN2FDPS | |
| SCHEMBL7868793 | 0.78 | CA2 (0.48) | CA2DNM1TSHRFDPSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960333-A1 | COMPOSITION FOR INHIBITING GENE EXPRESSION AND USES THEREOF | Idera Pharmaceuticals, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |