SCHEMBL17366367

SCHEMBL17366367

Fc1cccc(C2CCC(C3CCCCC3)CC2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.44
HDAC4 P56524 2/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
LMNA P02545 1/20 0.39
HCRTR2 O43614 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MLYCD O95822 1/20 0.38
PARP10 Q53GL7 1/20 0.38
RIPK1 Q13546 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
SCD5 Q86SK9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130265 0.89 KMO (0.53) KMOHDAC4HDAC2HDAC8HTR2A
SCHEMBL27830967 0.89 KMO (0.53) KMOHDAC4HDAC2HDAC8HTR2A
Hydrochloric Acid SCHEMBL28067220 0.87 KMO (0.51) KMOHDAC4HDAC2HDAC8HTR2A
SCHEMBL30704252 0.87 HDAC4 (0.52) KMOHDAC4HDAC2HDAC8HTR2A
SCHEMBL777204 0.87 HDAC4 (0.52) KMOHDAC4HDAC2HDAC8HTR2A
SCHEMBL29878889 0.87 HTR2C (0.47) HDAC4HDAC2HDAC8HTR2AHTR2C
SCHEMBL1515236 0.87 HTR2C (0.47) HDAC4HDAC2HDAC8HTR2AHTR2C
SCHEMBL10091161 0.84 ESR2 (0.42) HDAC4HTR2AHTR2CHTR2BHCRTR2
SCHEMBL353609 0.83 HDAC4 (0.47) KMOHDAC4HDAC2HDAC8HTR2A
SCHEMBL8753507 0.80 KDM1A (0.42) HTR2AHTR2CHTR2BHCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2960316-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC Corporation (JP) 2015-12-30 EP disclosed