Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907700 | 0.91 | ALDH1A1 (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2328368 | 0.89 | CA1 (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL17806188 | 0.88 | ALDH1A1 (0.52) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL16572363 | 0.87 | CA12 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL19003451 | 0.86 | ACACB (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15391900 | 0.86 | CA12 (0.63) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL17974332 | 0.85 | CA12 (0.66) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6283213 | 0.85 | CA1 (0.55) | CA1CA2KMT2AMEN1LMNA | |
| SCHEMBL1541945 | 0.84 | CA1 (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL13185193 | 0.84 | CA12 (0.67) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856224-B2 | Stable sodium channel blockers | PARION SCIENCES, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170267649-A1 | STABLE SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-20150376145-A1 | STABLE SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376145-A1 | STABLE SODIUM CHANNEL BLOCKERS | SCN1B, SCN2B, CACNA1B | CA12 1686/4885CA1 1880/4885CA2 241/4885 |
| US-20170267649-A1 | STABLE SODIUM CHANNEL BLOCKERS | SCN1B, SCN2B, CACNA1B | CA12 1686/4885CA1 1880/4885CA2 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.