SCHEMBL17367124

SCHEMBL17367124

c1ccc(-n2c3ccccc3c3c4c(ccc5c6ccccc6n(-c6ccc7ccccc7c6)c54)sc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PMM2 O15305 1/20 0.34
MPI P34949 1/20 0.34
PHOSPHO1 Q8TCT1 1/20 0.34
HPGD P15428 1/20 0.34
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
PRSS1 P07477 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDE1B Q01064 1/20 0.30
PDE3A Q14432 1/20 0.30
PDE11A Q9HCR9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17367040 0.86 KDM4E (0.39) KDM4EATML3MBTL1PMM2MPI
SCHEMBL17367107 0.86 KDM4E (0.41) KDM4EATML3MBTL1PMM2MPI
SCHEMBL15073715 0.84 KDM4E (0.49) KDM4EATML3MBTL1PMM2MPI
SCHEMBL17451664 0.84 KDM4E (0.47) KDM4EATML3MBTL1PMM2MPI
SCHEMBL10014542 0.83 PMM2 (0.40) KDM4EATML3MBTL1PMM2MPI
SCHEMBL23204243 0.83 KDM4E (0.49) KDM4EATML3MBTL1PMM2MPI
SCHEMBL23233714 0.83 KDM4E (0.49) KDM4EATML3MBTL1PMM2MPI
SCHEMBL15126698 0.82 PMM2 (0.35) KDM4EATML3MBTL1PMM2MPI
SCHEMBL17367127 0.82 PMM2 (0.38) KDM4EATML3MBTL1PMM2MPI
SCHEMBL18868249 0.82 KDM4E (0.38) KDM4EATML3MBTL1PMM2MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ATM 3202/4885L3MBTL1 717/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ATM 3202/4885L3MBTL1 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.