Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734444 | 0.97 | KDM4E (0.55) | KDM4ELMNASMN1; SMN2GLAGAA | |
| SCHEMBL1735209 | 0.93 | NPC1 (0.49) | KDM4EHRH3KMT2ANPC1RAB9A | |
| SCHEMBL1735211 | 0.89 | KDM4E (0.58) | KDM4ELMNASMN1; SMN2GLAKMT2A | |
| SCHEMBL1734298 | 0.88 | DRD3 (0.48) | KDM4ELMNASMN1; SMN2GLAHRH3 | |
| SCHEMBL13605415 | 0.87 | KDM4E (0.50) | KDM4ELMNASMN1; SMN2GLAHRH3 | |
| SCHEMBL1735223 | 0.87 | S1PR5 (0.52) | KDM4ELMNASMN1; SMN2GLAHRH3 | |
| SCHEMBL13605401 | 0.86 | LMNA (0.65) | KDM4ELMNASMN1; SMN2GLAGAA | |
| SCHEMBL13605333 | 0.85 | LMNA (0.47) | LMNASMN1; SMN2GLAKMT2AFLT3 | |
| SCHEMBL1735198 | 0.84 | AVPR1B (0.48) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL1735437 | 0.84 | KDM4E (0.49) | KDM4ELMNASMN1; SMN2GLAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928236-B1 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC (BM) | 2011-11-23 | — | — | EP | claimed |