SCHEMBL17367803

SCHEMBL17367803

c1ccc(-c2cccc(-c3cc(-c4cc(-c5cc6ccccc6cn5)cc(-c5cc6ccccc6cn5)c4)nc(-c4cccc(-c5ccccc5)c4)n3)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 3/20 0.49
MAPT P10636 3/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 2/20 0.49
LMNA P02545 2/20 0.49
NPC1 O15118 4/20 0.46
RAB9A P51151 2/20 0.46
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
MAOB P27338 2/20 0.43
GLA P06280 1/20 0.42
KMO O15229 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
NTSR1 P30989 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17343378 0.97 NPC1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17944936 0.95 NPC1 (0.53) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17413759 0.94 MEN1 (0.56) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL18858310 0.92 NPC1 (0.53) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17944926 0.92 NPC1 (0.53) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17343256 0.92 NPC1 (0.47) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL128015 0.90 NPC1 (0.54) KDM4ENPC1RAB9AIDO1TDO2
SCHEMBL17343381 0.89 NPC1 (0.55) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL18327524 0.89 NPC1 (0.51) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17343432 0.89 NPC1 (0.47) MEN1KMT2AKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9978955-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-22 US disclosed
US-9978955-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-22 US disclosed
US-20150380662-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380662-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed