Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.63 |
| ▸ | TK2 | O00142 | 3/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152125 | 1.00 | PYGM (0.63) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL16152124 | 0.90 | PYGM (0.60) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL41141 | 0.88 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL17012263 | 0.88 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL41142 | 0.88 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL14853822 | 0.88 | PYGM (0.66) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL22028243 | 0.86 | PYGM (0.67) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2754231 | 0.86 | PYGM (0.71) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL2754232 | 0.86 | PYGM (0.71) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL600801 | 0.86 | PYGM (0.64) | PYGMTK2SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157573-A2 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | Moderna Therapeutics, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015196128-A2 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-12-23 | — | — | WO | disclosed |
| US-9012453-B2 | Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia | H. LUNDBECK A/S (DK) | 2015-04-21 | — | — | US | disclosed |