Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.40 |
| ▸ | USP2 | O75604 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737816 | 0.99 | ROCK2 (0.42) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| SCHEMBL1738897 | 0.91 | USP2 (0.48) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| Hydrochloric Acid SCHEMBL1738700 | 0.90 | USP2 (0.47) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| SCHEMBL1737700 | 0.90 | ROCK2 (0.45) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| Hydrochloric Acid SCHEMBL1736940 | 0.89 | ROCK2 (0.45) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| SCHEMBL1737535 | 0.89 | USP2 (0.48) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| SCHEMBL1738220 | 0.88 | USP2 (0.50) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| SCHEMBL1738227 | 0.88 | CYP3A4 (0.50) | ROCK2CYP1A2CYP3A4CYP2C9USP2 | |
| SCHEMBL1738133 | 0.88 | CYP11B1 (0.38) | ALDH1A1MAPTCASRTP53MEN1 | |
| Hydrochloric Acid SCHEMBL1736592 | 0.88 | USP2 (0.47) | ROCK2CYP1A2CYP3A4CYP2C9USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |