Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371725 | 0.86 | LMNA (0.39) | ALDH1A1LMNACHRM2CHRM1 | |
| SCHEMBL15824200 | 0.86 | CYP1A2 (0.38) | POLBALDH1A1LMNAADORA3MAPK1 | |
| SCHEMBL15210247 | 0.70 | MARK3 (0.46) | HTR2AHTR2CHTR2BPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL15205942 | 0.69 | MARK3 (0.45) | HTR2AHTR2CHTR2BPOLBALDH1A1 | |
| SCHEMBL13769940 | 0.69 | PDK2 (0.40) | HTR2AHTR2CHTR2BPOLBALDH1A1 | |
| SCHEMBL30317055 | 0.68 | HTR2C (0.43) | EPHX2HTR2AHTR2CHTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL4005503 | 0.68 | PDK4 (0.39) | HTR2AHTR2CHTR2BPOLBALDH1A1 | |
| SCHEMBL1198542 | 0.67 | MAPK1 (0.44) | HTR2AHTR2CHTR2BPOLBALDH1A1 | |
| SCHEMBL13999790 | 0.65 | MAPK1 (0.39) | HTR2AHTR2CHTR2BLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL5107756 | 0.64 | MAPK1 (0.38) | HTR2AHTR2CHTR2BLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157919-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015193219-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |