Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736669 | 0.99 | HTR2A (0.34) | HTR2AHTR2CCCNB2CDK1CCNB1 | |
| SCHEMBL1737805 | 0.92 | CCNB2 (0.34) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL1739182 | 0.91 | CCNB2 (0.33) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL1735825 | 0.91 | CCNB2 (0.33) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL1739177 | 0.91 | CCNB2 (0.33) | CCNB2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL1738210 | 0.88 | HTR2B (0.35) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1736939 | 0.87 | HTR2B (0.34) | HTR2AHTR2CCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1737600 | 0.86 | DYRK1A (0.43) | HTR2AHTR2CCCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL1737011 | 0.85 | DYRK1A (0.42) | HTR2AHTR2CCCNB2CDK1CCNB1 | |
| SCHEMBL1735608 | 0.85 | MAPT (0.37) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |