Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736939 | 0.99 | HTR2B (0.34) | HTR2BHTR2AHTR2CADRB1HTR1A | |
| SCHEMBL1737475 | 0.88 | HTR2A (0.35) | HTR2AHTR2CCYP2C19CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1736669 | 0.87 | HTR2A (0.34) | HTR2AHTR2CCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL1737600 | 0.86 | DYRK1A (0.43) | HTR2BHTR2AHTR2CADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL1737011 | 0.85 | DYRK1A (0.42) | HTR2BHTR2AHTR2CADRA2AADRA2B | |
| SCHEMBL1735608 | 0.85 | MAPT (0.37) | HTR2BHTR2AHTR2CHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL1736651 | 0.84 | KDM4E (0.36) | HTR2BHTR2AHTR2CHTR1AADRA2A | |
| SCHEMBL1736981 | 0.84 | KDM4E (0.36) | HTR2BHTR2AHTR2CHTR1AADRA2A | |
| SCHEMBL1736979 | 0.84 | MAPT (0.36) | HTR2BHTR2AHTR2CHTR1AADRA2A | |
| SCHEMBL1737805 | 0.81 | CCNB2 (0.34) | CYP2C19CYP1A2CYP3A4CYP2C9DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |