Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.48 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411404 | 0.93 | SMN1; SMN2 (0.49) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL23420873 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL31634157 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL28709647 | 0.83 | TSHR (0.51) | ALDH1A1TSHRSMN1; SMN2TDP1MEN1 | |
| SCHEMBL395354 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL17375025 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL17374959 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL7937707 | 0.81 | SNCA (0.55) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL29510944 | 0.81 | SNCA (0.55) | ALDH1A1TSHRSMN1; SMN2ALOX15TDP1 | |
| SCHEMBL1465151 | 0.79 | TSHR (0.47) | ALDH1A1TSHRSMN1; SMN2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106065009-B | Application as the compound of hepatitis c inhibitor and its in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |