Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.30 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17375076 | 0.88 | CYP3A4 (0.36) | CYP3A4CRBNDDB1 | |
| SCHEMBL17378859 | 0.86 | CRBN (0.38) | CYP3A4CRBNDDB1AURKBHTR7 | |
| SCHEMBL17378945 | 0.86 | CYP3A4 (0.36) | CYP3A4CRBNDDB1AURKB | |
| SCHEMBL1530350 | 0.83 | CYP3A4 (0.56) | CYP3A4CRBNTRPV1DDB1TDP2 | |
| SCHEMBL1530351 | 0.83 | CYP3A4 (0.56) | CYP3A4CRBNTRPV1DDB1TDP2 | |
| SCHEMBL1530391 | 0.83 | CYP3A4 (0.56) | CYP3A4CRBNTRPV1DDB1TDP2 | |
| SCHEMBL17378791 | 0.83 | CRBN (0.36) | CYP3A4CRBNDDB1TDP2 | |
| SCHEMBL17375035 | 0.81 | CRBN (0.50) | CYP3A4CRBNDDB1TDP2NR3C2 | |
| SCHEMBL17378862 | 0.79 | CRBN (0.38) | CRBNDDB1 | |
| SCHEMBL17375001 | 0.78 | GAA (0.36) | CYP3A4CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |