Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378859 | 0.92 | CRBN (0.38) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL17375008 | 0.86 | CYP3A4 (0.47) | CYP3A4CRBNAURKBDDB1 | |
| SCHEMBL1530629 | 0.84 | CYP3A4 (0.40) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL1530628 | 0.84 | CYP3A4 (0.40) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL1530625 | 0.84 | CYP3A4 (0.40) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL17378791 | 0.81 | CRBN (0.36) | CYP3A4CRBNDDB1 | |
| SCHEMBL1530475 | 0.79 | CYP3A4 (0.40) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL1530502 | 0.79 | CYP3A4 (0.40) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL1530479 | 0.79 | CYP3A4 (0.40) | CYP3A4CRBNAURKBWDR5DDB1 | |
| SCHEMBL17375035 | 0.79 | CRBN (0.50) | CYP3A4CRBNAURKBDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |