Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451704 | 1.00 | MAPT (0.49) | MAPTL3MBTL1SMN1; SMN2POLBTPMT | |
| SCHEMBL31451909 | 0.84 | MAPT (0.39) | MAPTL3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL17375039 | 0.84 | MAPT (0.39) | MAPTL3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL31451828 | 0.84 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2POLBTPMTKMT2A | |
| SCHEMBL1068541 | 0.84 | MAPT (0.50) | MAPTL3MBTL1SMN1; SMN2POLBTPMT | |
| SCHEMBL17378861 | 0.81 | ALDH1A1 (0.53) | L3MBTL1SMN1; SMN2TPMTKMT2AMEN1 | |
| SCHEMBL17045501 | 0.81 | GRIN2D (0.47) | MAPTL3MBTL1POLBTPMTKMT2A | |
| SCHEMBL1868433 | 0.80 | ALDH1A1 (0.41) | MAPTL3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL31381636 | 0.79 | CYP1A2 (0.41) | MAPTL3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL13277488 | 0.79 | CYP1A2 (0.41) | MAPTL3MBTL1SMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |