Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139004 | 0.87 | SMYD2 (0.40) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL31139029 | 0.87 | SMYD2 (0.40) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL10004139 | 0.87 | SMYD2 (0.40) | SMYD2HTTCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6660786 | 0.87 | SMYD2 (0.40) | SMYD2HTTCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL224828 | 0.87 | SMYD2 (0.40) | SMYD2HTTCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL31276323 | 0.87 | SMYD2 (0.40) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL9841198 | 0.85 | SMYD2 (0.39) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL4402734 | 0.85 | SMYD2 (0.41) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL17913545 | 0.84 | SMYD2 (0.39) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 | |
| SCHEMBL14481194 | 0.84 | SMYD2 (0.39) | SMYD2HTTCYP3A4SMN1; SMN2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157929-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | Tocopherx, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015196759-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX, INC. (US) | 2015-12-30 | — | — | WO | disclosed |