Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737219 | 0.99 | CYP1A2 (0.35) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| SCHEMBL1735608 | 0.86 | MAPT (0.37) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| Hydrochloric Acid SCHEMBL1736651 | 0.85 | KDM4E (0.36) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| SCHEMBL1736981 | 0.85 | KDM4E (0.36) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| SCHEMBL1736979 | 0.85 | MAPT (0.36) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| SCHEMBL1739132 | 0.83 | DYRK1A (0.34) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| Hydrochloric Acid SCHEMBL1735984 | 0.82 | DYRK1A (0.34) | CYP1A2CYP2C9CYP2C19CYP3A4DYRK1A | |
| SCHEMBL1737164 | 0.82 | HTR1A (0.35) | CYP1A2CYP2C9CYP2C19CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL1736164 | 0.81 | HTR1A (0.35) | CYP1A2CYP2C9CYP2C19CHRM2HTR1A | |
| SCHEMBL1737283 | 0.79 | MEN1 (0.35) | CYP1A2CYP2C9CYP2C19CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |